The game continues the story of Abe, charting his efforts to save his fellow Mudokons from another plot by the Glukkons to exploit them. Abe discovers that the Glukkons are enslaving Mudokons, this time to produce a drink called Soulstorm Brew, which uses Mudokon bones and tears as its ingredients. Abe must travel to the Soul Storm Brewery, stop those corporate villains and save the enslaved Mudokon workers.